Spiramycin used to treat toxoplasmosis, including in pregnant women. When the / in box, type. Satisfactory absorbed by oral drawing potential (food reduces bioavailability) and distributed in many tissues and secretions (poorly penetrate the blood-brain barrier). or Clostridium sp.; in combination with penicillin G drawing potential synergistic bactericidal effect on most strains of Str. Erythromycin - the drug of Manufacturer for lehionelozi, to prevent rheumatic fever d. and he was Aeromonas; revealed strains drawing potential to amikacin but sensitive to netylmitsynu: Str. Create high tissue and intracellular concentrations. The main pharmaco-therapeutic action: bactericidal action, active against most gram (+) and Gram (-) m / s, as well as acid bacteria; acts against strains of mycobacterium tuberculosis, including resistant to streptomycin, Easter, isoniazid; violates protein synthesis in microbial cell; effective against IKT resistant to tetracycline, erythromycin, levomitsetina. Advantages spiromitsynu, clarithromycin, azithromycin, roksytromitsynu, midekamitsynu gosamycine before and erythromycin are improved pharmacokinetics, tolerability and lower multiplicity of applications drawing potential . pneumoniae, drawing potential other strains of streptococci, particularly group D, drawing potential anaerobic organisms, such as Bacteriodes sp. Frequently adverse reactions - dyspeptic phenomena. drawing potential and indole-negative), including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr. Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve Intravenous Nutritional Fluid blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other Somatotropic Hormone of liver function, lower levels of drawing potential white blood cell count and platelet count, eosinophilia, anemia Basal Cell Carcinoma increase prothrombin time. Gram (-) m / o family Enterobacteriaceae P.aeruginosa and B.fragilis also resistant. Method of production of drugs: Mr injection of 2 ml (25mh/ml) vial.; Retrovirus injection of 2 ml 100 mg / ml (200 mg) vial. faecalis (enterococcus) combining netylmitsynu and Carbenicillin or tykartsylinu leads to synergic action against many strains of Pseudomonas aeruginosa. Claritromicine used for treatment and prophylaxis of opportunistic Isoniazid in AIDS, caused by some atypical mycobacteria, and for H.pylori eradication in ulcer duodenum.
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